Diosmin
 | |
| KliniΔki podaci | |
|---|---|
| Drugs.com | Monografija |
| Identifikatori | |
| CAS broj | 520-27-4  |
| ATC kod | C05CA03 (WHO) |
| PubChem | CID 5281613 |
| ChemSpider | 4444932 |
| UNII | 7QM776WJ5N |
| KEGG | D07858 |
| ChEMBL | CHEMBL231884 |
Diosmin je organsko jedinjenje, koje sadrΕΎi 28 atoma ugljenika i ima molekulsku masu od 608,545 Da.
Osobine
[ΡΡΠ΅Π΄ΠΈ | ΡΡΠ΅Π΄ΠΈ ΠΈΠ·Π²ΠΎΡ]| Osobina | Vrednost |
|---|---|
| Broj akceptora vodonika | 15 |
| Broj donora vodonika | 8 |
| Broj rotacionih veza | 7 |
| Particioni koeficijent[1] (ALogP) | -0,4 |
| Rastvorljivost[2] (logS, log(mol/L)) | -2,7 |
| Polarna povrΕ‘ina[3] (PSA, Γ 2) | 234,3 |
Reference
[ΡΡΠ΅Π΄ΠΈ | ΡΡΠ΅Π΄ΠΈ ΠΈΠ·Π²ΠΎΡ]- ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). βPrediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methodsβ. J. Phys. Chem. A. 102: 3762β3772. doi:10.1021/jp980230o.
- ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). βEstimation of Aqueous Solubility of Chemical Compounds Using E-State Indicesβ. Chem Inf. Comput. Sci.. 41: 1488β1493. PMID 11749573. doi:10.1021/ci000392t.
- ^ Ertl P.; Rohde B.; Selzer P. (2000). βFast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport propertiesβ. J. Med. Chem.. 43: 3714β3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura
[ΡΡΠ΅Π΄ΠΈ | ΡΡΠ΅Π΄ΠΈ ΠΈΠ·Π²ΠΎΡ]- Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. ΠΈΠ·Π΄.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
- Thomas L. Lemke; David A. Williams, ΡΡ. (2007). Foye's Principles of Medicinal Chemistry (6. ΠΈΠ·Π΄.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.
SpoljaΕ‘nje veze
[ΡΡΠ΅Π΄ΠΈ | ΡΡΠ΅Π΄ΠΈ ΠΈΠ·Π²ΠΎΡ]- Diosmin ΠΡΡ ΠΈΠ²ΠΈΡΠ°Π½ΠΎ Π½Π° Π²Π΅Π±-ΡΠ°ΡΡΡ Wayback Machine (5. ΡΠ΅ΠΏΡΠ΅ΠΌΠ±Π°Ρ 2018)
 | Molimo Vas, obratite paΕΎnju na vaΕΎno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
