Mistral Large 4 (Le Chonk): Run Locally
Guide to running Mistral Large 4 GGUFs locally with Unsloth and llama.cpp.
Mistral Large 4 (Le Chonk) is Mistralโs 1 trillion parameter MoE model with 52B active parameters (including embeddings and output layers). Mistral Large 4 is the strongest Western open model to date and supports text and image inputs, a 1M-context window, 160+ languages, and reasoning. You can run Le Chonk locally with Unsloth Dynamic GGUFs via Unsloth or llama.cpp. GGUF: Mistral-Large-4-1T-A52B-GGUF
Dynamic 1bit retains 91% of top-1 accuracy across coding, agentic tasks, math and other areas whilst being 80% smaller (223GB vs 1.1TB FP8). Dynamic 2bit retains 95% top-1 accuracy whilst 66% smaller (378GB). Thank you Mistral for day zero access.
โ๏ธ Usage Guide
The smallest Dynamic 1-bit quant, UD-IQ1_S, uses approximately 233GB of disk space which should fit on 256GB RAM including a Mac Studio or 2x NVIDIA DGX Sparks.
Table: Hardware requirements (units = total memory: RAM + VRAM, or unified memory)
256โ270GB
310โ390GB
435โ500GB
630GB
1.2TB
For best performance, your total available RAM + VRAM, or unified memory, should exceed the quantโs file size with room for the operating system, KV cache and runtime buffers. Longer contexts need more memory.
Recommended Settings
Mistral recommends the same sampling settings for all reasoning efforts:
1.0
0.95
Reasoning efforts = low, medium, and high
Maximum context window is
1,048,576tokens.
We also ran KLD benchmarks for all quants - more details in Quantization Analysis

Run Mistral Large 4 Tutorials:
The examples below use UD-Q2_K_XL for text inference. You can change the quantization type to any available quant in the GGUF repository.
๐ฆฅ Run Mistral Large 4 in Unsloth
Unsloth Desktop runs GGUFs locally on macOS, Windows and Linux, automatically offloads to RAM and detects multi-GPU setups.
Install Unsloth
The easiest way to get started is by downloading the Unsloth Desktop app. Works on macOS, Windows, and Linux.
Or, if you prefer to install manually:
MacOS, Linux, WSL:
Windows PowerShell:
Search and download Mistral Large 4
Go to Unsloth Chat or Model hub, search for Mistral-Large-4-1T-A52B and select unsloth/Mistral-Large-4-1T-A52B-GGUF. Download your desired quant using the sizes and memory requirements above.
Run Mistral Large 4
Mistral Large 4 uses high reasoning effort by default. Use low for fast chat, medium for everyday tasks, or high for complex prompts and agentic coding. Unsloth automatically selects the best configurations for you but you can still adjust manually.
For more information, you can view our Unsloth inference guide.
Serve Mistral Large 4 with Unsloth API
You can use the unsloth run command to serve Mistral Large 4 via an API using llama-server runtime flags, including context sizing, GPU layers, threading and sampling. For more info see our API docs or unsloth start.
Use a runtime with Mistral Large 4 support.
Unsloth is now ready
You can connect Mistral Large 4 to your tools through Unsloth Desktop. Unsloth also supports the following workflows:
Connect tools: Claude Code, Codex, web search, MCP and more
Train models: Fine-tune other supported text, diffusion, embedding, and more

Quantization Analysis
We ran KLD and top-1% benchmarks across a variety of areas like tool calling, coding and agentic long traces, and show that Unsloth dynamic quantization (UD3) can retain a lot of accuracy whilst still making the model smaller.

We also ran KLD and provide it per corpus as well:

๐ฆ Run Mistral Large 4 in llama.cpp
Use a llama.cpp build with Mistral Large 4 support. The commands below use the UD-Q2_K_XL quant (approximately 378GB).
Install llama.cpp
Obtain llama.cpp on GitHub, or build it below. On Linux with an NVIDIA GPU, install the CUDA toolkit and build dependencies first:
For CPU or Apple Metal, use -DGGML_CUDA=OFF. Metal support is enabled by default on macOS. For Windows and other GPU backends, follow the repositoryโs build instructions.
Download and run Mistral Large 4
This command downloads the quant and starts a local chat server:
Open http://127.0.0.1:8080 in your browser to chat. The API is available at http://127.0.0.1:8080/v1.
The example uses a 32K context to limit KV-cache memory. --top-k 0 and --min-p 0.0 disable additional sampling filters so the recommended temperature and top-p settings apply. If you run out of memory, lower --ctx-size or choose a smaller quant.
Optional: download manually
Install the Hugging Face CLI and download only the quant you want:
Keep all 9 shards in the same directory. In the server command above, replace -hf unsloth/Mistral-Large-4-1T-A52B-GGUF:UD-Q2_K_XL with:
llama.cpp loads the remaining shards automatically. To use Dynamic 1-bit instead, download UD-IQ1_S/* and point --model at Mistral-Large-4-1T-A52B-UD-IQ1_S-00001-of-00006.gguf in that folder.
Benchmarks
More benchmarks are listed in Mistral's official blog.




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