Haematin Explained

Haematin (also known as hematin, ferriheme, hematosin, hydroxyhemin, oxyheme, phenodin, or oxyhemochromogen) is a dark bluish or brownish pigment containing iron in the ferric state, obtained by the oxidation of haem.

Haematin inhibits the synthesis of porphyrin (by repressing ALAS1 synthesis),[1] and stimulates the synthesis of globin. For this reason, it is used in the treatment of porphyrias.

It is a component of cytochromes and peroxidases. Haematin derived synthetically from hemin is used as a reagent.

Notes and References

  1. Book: Rodwell, Victor W. . Harper's Illustrated Biochemistry . McGraw-Hill Education . 2018 . 978-1-25-983794-4 . 31st . 311.