Pyrimidone Explained

Pyrimidone is the name given to either of two heterocyclic compounds with the formula C₄H₄N₂O: 2-pyrimidone^[1] and 4-pyrimidone. The compounds can also be called 2-hydroxypyrimidine or 4-hydroxypyrimidine respectively, based on a substituted pyrimidine, or 1,3-diazine, ring.

Applications

Energy storage

Chemists at UC Santa Barbara have determined that pyrimidone can be used for reversible, stable, long term thermal energy storage with an energy density of 1.6 MJ/kg^[2], approximately double that of a lithium ion battery.

Derivatives

Derivatives of pyrimidone are the basis of many other biological molecules, including:

• Nucleobases, such as cytosine
• Barbiturates, such as metharbital

• Antiulcer drugs including temelastine, icotidine, donetidine, and lupitidine.

Notes and References

1. Book: Manglik . Mr Rohit . Basics of Organic Chemistry . 23 June 2023 . EduGorilla Publication . 978-93-6817-864-4 . 430 . en.
2. Nguyen . Han P. Q. . Maertens . Alexander J. . Baker . Benjamin A. . Wu . Nathan M.-W. . Ye . Zihao . Zhou . Qingyang . Qiu . Qianfeng . Kaur . Navneet . Berkinsky . David B. . Shulenberger . Katherine E. . Houk . K. N. . Han . Grace G. D. . 2026-02-12 . Molecular solar thermal energy storage in Dewar pyrimidone beyond 1.6 MJ/kg . Science . 0 . 0 . eaec6413 . 10.1126/science.aec6413. subscription .