| Sa Kaeo | |
| Settlement Type: | Town |
| Pushpin Map: | Thailand |
| Subdivision Type: | Country |
| Subdivision Name: | Thailand |
| Subdivision Type1: | Province |
| Subdivision Name1: | Sa Kaeo province |
| Subdivision Type2: | District |
| Subdivision Name2: | Mueang Sa Kaeo district |
| Population As Of: | 2005 |
| Population Total: | 16,591 |
| Timezone: | ICT |
| Utc Offset: | +7 |
| Coordinates: | 13.8206°N 102.0589°W |
Sa Kaeo (th|สระแก้ว, pronounced as /th/) is a town (thesaban mueang) in Thailand, about 48 kilometers from the Thai-Cambodian border and 200 km east of Bangkok. It is the capital of Sa Kaeo province. As of 2005, it had a population of 16,591. The town covers 11 sub-districts (tambon).
From 1979–1980, Sa Kaeo was the site of the Sa Kaeo Refugee Camp.
